MyBioSource.com's ATXN3 Polyclonal Antibody is a Goat Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The ATXN3 Polyclonal Antibody was generated using Ataxin 3, ATX3, ATXN3, JOS, and MJD as the antigen and it reacts with Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Non-Human Primate, Porcine, Rabbit, and Sheep.
Description
Ataxin 3
Goat polyclonal antibody to ATXN3. This protein appears to be a component of the ubiquitin proteasome system and has deubiquitinase activity. It may also have roles in neuroprotection, protein homeostasis maintenance, transcriptional and cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The protein contains Qn repeats in the coding region, and the expansion of these repeats from the normal 13-36 to 68-79 is one cause of Machado-Joseph disease also known as spinocerebellar ataxia-3, an autosomal dominant neurologic disorder